Isom Place, located at 1003 Jefferson Avenue, is one of Oxford’s oldest and most historic homes.
1003 Jefferson Avenue
Bedrooms on 1st Floor
# of People
Walk to Campus
Walk to Square
OUT Bus Stop
Although some say the greek-revival Southern mansion was built by Dr.
Thomas Dudley Isom, the first white settler at the present site of
Oxford, others dispute this claim.
According to my friend and fellow Oxford historian Jack Case Wilson,
the home as it now stands was actually built by the Carothers family in
the 1840s, although a log structure inside may have existed previously.
“Samuel Carothers bought the lot in 1843, built the house in 1844, then
died in 1845, as referenced in his will at the courthouse,” Wilson
explained. “Isom bought it around 1847.”
The structure, which served as Dr. Isom’s home, office and
apothecary, was expanded in 1862. The charter of the University of
Mississippi was signed in its dining room. Following Dr. Isom’s death in
1902, the house was sold several times and many minor additions were
made before it was bought by Dr. and Mrs. H. D. Worthy in 1960 and
returned to its 1920-era appearance.
In 1995, Susan Barksdale bought the house and renovated it as a bed
& breakfast. It is now known as the Barksdale-Isom House. Since
2000, the building has housed the Barksdale Reading Institute. The
Barksdale Reading Institute is designed to improve significantly the
pre-literacy and reading skills of Mississippi’s children from birth
through the 3rd grade.
Isom Place was declared a National Historic Place in March 1975.
John Cofield, via HottyToddy.com
The Barksdale Reading Institute offices are located upstairs. Downstairs, much of the bed and breakfast remains. There are three bedrooms, each with a private bath, along with another half bath. The large commercial kitchen and dining room and the living room may be used by weekend guests.
Sleeps 6 with 2 king beds and 1 queen bed.